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KMID : 0861420100140020145
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Korean Journal of Nuclear Medicine Technology
2010 Volume.14 No. 2 p.145 ~ p.149
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Usefulness of 18F-FDG Fusion PET for Diagnosing an Early Stage Cancer
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Jeon Jae-Hwan
Kim Byung-Jin
Lee Hong-Jae
Kim Jin-Eui
Kim Hyun-Joo
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Abstract
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Purpose: Recently, 18F-FDG Fusion PET which has a high sensitivity for diagnosing cancer is being used for purpose of health examination. This study is to demonstrate that 18F-FDG fusion PET study is useful for diagnosing an early stage cancer.
Materials and Methods: This research has been conducted with 2790 patients visited Seoul National University Hospital Healthcare System (SNUHHS) for 18F-FDG fusion PET study for a health examination from February, 2004 to December 2008. PET/CT images were acquired from skull base to femur after 1 hour from injecting 18F-FDG 0.14 mCi/kg to the patients. GEMINI GS (Philips, Netherlands) was used for scanning.
Results: From February 2004 to December 2008, 18F-FDG Fusion PET study was performed for 99,009 patients among all patients who visited SNUHHS and 2,790 patients was performed. Diagnostic rate for malignant cancer was 0.95% for the patients who were not examined by 18F-FDG Fusion PET study. 1.94% was for the patients who were. The rate of malignant tumor was showed 10% and benign tumor was 90% among 542 patients who showed abnormality in the PET/CT images. Types and rates of malignant tumor showed thyroid cancer: 31.5%, lung cancer: 14.8%, stomach cancer: 9.3%, rectum cancer: 3.7%, breast cancer: 3.7%, metastasis cancer: 16.7%. Nonspecific lymph node in the mediastinum, physiologic uptake in the colon, diffuse mild hypermetabolism in bilateral thyroid gland were shown as a benign tumor.
Conclusion: The diagnostic rate of malignant tumor with 18F-FDG Fusion PET for a purpose of health examination was relatively higher than general medical examination. Consequently, it is superior and useful for applying 18F-FDG Fusion PET study for health examination.
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KEYWORD
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18F-FDG Fusion PET , health examination , early stage cancer
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